Python Github Star Ranking at 2016/08/31
jkbrzt/httpie                              22886
CLI HTTP client, user-friendly curl replacement with intuitive UI, JSON support, syntax highlighting, wget-like downloads, extensions, etc.
vinta/awesome-python                       21291
A curated list of awesome Python frameworks, libraries, software and resources
pallets/flask                              20753
A microframework based on Werkzeug, Jinja2 and good intentions
nvbn/thefuck                               20421
Magnificent app which corrects your previous console command.
django/django                              19703
The Web framework for perfectionists with deadlines.
kennethreitz/requests                      19233
Python HTTP Requests for Humans™
rg3/youtube-dl                             18179
Small command-line program to download videos from YouTube.com and other video sites
ansible/ansible                            17098
Ansible is a radically simple IT automation platform that makes your applications and systems easier to deploy. Avoid writing scripts or custom code to deploy and update your applications— automate in a language that approaches plain English, using SSH, with no agents to install on remote systems.
certbot/certbot                            15212
Certbot, previously the Let's Encrypt Client, is EFF's tool to obtain certs from Let's Encrypt, and (optionally) auto-enable HTTPS on your server.  It can also act as a client for any other CA that uses the ACME protocol.
scrapy/scrapy                              14341
Scrapy, a fast high-level web crawling & scraping framework for Python.
josephmisiti/awesome-machine-learning      13370
A curated list of awesome Machine Learning frameworks, libraries and software.
shadowsocks/shadowsocks                    13082
scikit-learn/scikit-learn                  11690
scikit-learn: machine learning in Python
tornadoweb/tornado                         11491
Tornado is a Python web framework and asynchronous networking library, originally developed at FriendFeed.
minimaxir/big-list-of-naughty-strings      11464
The Big List of Naughty Strings is a list of strings which have a high probability of causing issues when used as user-input data.
isocpp/CppCoreGuidelines                   11082
The C++ Core Guidelines are a set of tried-and-true guidelines, rules, and best practices about coding in C++
Valloric/YouCompleteMe                     10915
A code-completion engine for Vim
reddit/reddit                              10866
the code that powers reddit.com
getsentry/sentry                           9274
Sentry is cross-platform crash reporting built with love
ipython/ipython                            9274
Official repository for IPython itself. Other repos in the IPython organization contain things like the website, documentation builds, etc.
adobe-fonts/source-code-pro                8607
Monospaced font family for user interface and coding environments
faif/python-patterns                       8541
A collection of design patterns/idioms in Python
chrissimpkins/Hack                         7977
A typeface designed for source code
docker/compose                             7646
Define and run multi-container applications with Docker
XX-net/XX-Net                              7624
a web proxy tool
fabric/fabric                              7211
Simple, Pythonic remote execution and deployment.
Rochester-NRT/RocAlphaGo                   6987
An independent, student-led replication of DeepMind's 2016 Nature publication, "Mastering the game of Go with deep neural networks and tree search" (Nature 529, 484-489, 28 Jan 2016), details of which can be found on their website https://deepmind.com/publications.html.
apenwarr/sshuttle                          6851
Transparent proxy server that works as a poor man's VPN.  Forwards over ssh.  Doesn't require admin.  Works with Linux and MacOS.  Supports DNS tunneling.
binux/pyspider                             6635
A Powerful Spider(Web Crawler) System in Python.
saltstack/salt                             6573
Software to automate the management and configuration of any infrastructure or application at scale. Get access to the Salt Open software package repository here: 
soimort/you-get                            6572
:arrow_double_down: Dumb downloader that scrapes the web
mailpile/Mailpile                          6500
A free & open modern, fast email client with user-friendly encryption and privacy features
fchollet/keras                             6403
Deep Learning library for Python. Convnets, recurrent neural networks, and more. Runs on Theano and TensorFlow.
pydata/pandas                              6387
Flexible and powerful data analysis / manipulation library for Python, providing labeled data structures similar to R data.frame objects, statistical functions, and much more
airbnb/caravel                             6304
Caravel is a data exploration platform designed to be visual, intuitive, and interactive
sqlmapproject/sqlmap                       6270
Automatic SQL injection and database takeover tool
p-e-w/maybe                                5939
 :open_file_folder: :rabbit2: :tophat: See what a program does before deciding whether you really want it to happen.
powerline/powerline                        5933
Powerline is a statusline plugin for vim, and provides statuslines and prompts for several other applications, including zsh, bash, tmux, IPython, Awesome and Qtile.
alexjc/neural-doodle                       5910
Turn your two-bit doodles into fine artworks with deep neural networks, generate seamless textures from photos, transfer style from one image to another, perform example-based upscaling, but wait... there's more! (An implementation of Semantic Style Transfer.)
tomchristie/django-rest-framework          5886
Web APIs for Django.
donnemartin/data-science-ipython-notebooks 5741
Continually updated data science Python notebooks: Deep learning (TensorFlow, Theano, Caffe), scikit-learn, Kaggle, big data (Spark, Hadoop MapReduce, HDFS), matplotlib, pandas, NumPy, SciPy, Python essentials, AWS, and various command lines.
deis/deis                                  5598
Your PaaS. Your Rules. 
tensorflow/models                          5542
Models built with TensorFlow
boto/boto                                  5483
For the latest version of boto, see https://github.com/boto/boto3 -- Python interface to Amazon Web Services
fxsjy/jieba                                5297
结巴中文分词
nicolargo/glances                          5154
Glances an Eye on your system
facebook/chisel                            4931
Chisel is a collection of LLDB commands to assist debugging iOS apps.
nate-parrott/Flashlight                    4857
The missing Spotlight plugin system
celery/celery                              4811
Distributed Task Queue (development branch)
mail-in-a-box/mailinabox                   4763
Mail-in-a-Box helps individuals take back control of their email by defining a one-click, easy-to-deploy SMTP+everything else server: a mail server in a box.
beetbox/beets                              4744
music library manager and MusicBrainz tagger
lra/mackup                                 4728
Keep your application settings in sync (OS X/Linux)
USArmyResearchLab/Dshell                   4691
Dshell is a network forensic analysis framework.
spotify/luigi                              4687
Luigi is a Python module that helps you build complex pipelines of batch jobs. It handles dependency resolution, workflow management, visualization etc. It also comes with Hadoop support built in. 
bup/bup                                    4543
Very efficient backup system based on the git packfile format, providing fast incremental saves and global deduplication (among and within files, including virtual machine images). Current release is 0.28, and the development branch is master. Please post problems or patches to the mailing list for discussion (see the end of the README below).
clips/pattern                              4497
Web mining module for Python, with tools for scraping, natural language processing, machine learning, network analysis and visualization.
dbcli/pgcli                                4432
Postgres CLI with autocompletion and syntax highlighting
kivy/kivy                                  4418
Open source UI framework written in Python, running on Windows, Linux, OS X, Android and iOS
gleitz/howdoi                              4418
howdoi - instant coding answers via the command line
odoo/odoo                                  4374
Odoo (formerly OpenERP). Open Source Apps To Grow Your Business.
drduh/OS-X-Security-and-Privacy-Guide      4368
A practical guide to securing OS X
HelloZeroNet/ZeroNet                       4356
ZeroNet - Decentralized websites using Bitcoin crypto and BitTorrent network
docopt/docopt                              4349
Pythonic command line arguments parser, that will make you smile
0x5e/wechat-deleted-friends                4318
查看被删的微信好友
wting/autojump                             4276
A cd command that learns - easily navigate directories from the command line
bokeh/bokeh                                4250
Interactive Web Plotting for Python
ajenti/ajenti                              4247
Ajenti Core and stock plugins
phusion/baseimage-docker                   4247
A minimal Ubuntu base image modified for Docker-friendliness
SublimeCodeIntel/SublimeCodeIntel          4225
Full-featured code intelligence and smart autocomplete engine
numenta/nupic                              4172
Numenta Platform for Intelligent Computing: a brain-inspired machine intelligence platform, and biologically accurate neural network based on cortical learning algorithms.
divio/django-cms                           4171
The easy-to-use and developer-friendly CMS
andymccurdy/redis-py                       4137
Redis Python Client
eliangcs/http-prompt                       4077
HTTPie + prompt_toolkit = an interactive command-line HTTP client featuring autocomplete and syntax highlighting
chriskiehl/Gooey                           4043
Turn (almost) any Python command line program into a full GUI application with one line
sophron/wifiphisher                        4042
Automated phishing attacks against Wi-Fi networks
kennethreitz/legit                         4001
Git for Humans, Inspired by GitHub for Mac™.
lebinh/ngxtop                              3989
Real-time metrics for nginx server
thumbor/thumbor                            3921
thumbor is an open-source photo thumbnail service by globo.com
facebookarchive/huxley                     3893
A testing system for catching visual regressions in Web applications.
aws/aws-cli                                3889
Universal Command Line Interface for Amazon Web Services
webpy/webpy                                3886
web.py is a web framework for python that is as simple as it is powerful. 
zulip/zulip                                3876
Zulip server - powerful open source group chat
Theano/Theano                              3868
Theano is a Python library that allows you to define, optimize, and evaluate mathematical expressions involving multi-dimensional arrays efficiently. It can use GPUs and perform efficient symbolic differentiation.
bottlepy/bottle                            3768
bottle.py is a fast and simple micro-framework for python web-applications.
harelba/q                                  3761
q - Run SQL directly on CSV or TSV files  
jlund/streisand                            3752
Streisand sets up a new server running L2TP/IPsec, OpenConnect, OpenSSH, OpenVPN, Shadowsocks, sslh, Stunnel, and a Tor bridge. It also generates custom configuration instructions for all of these services. At the end of the run you are given an HTML file with instructions that can be shared with friends, family members, and fellow activists.
dropbox/pyston                             3749
An open-source Python implementation using JIT techniques. 
joke2k/faker                               3745
Faker is a Python package that generates fake data for you.
matplotlib/matplotlib                      3697
matplotlib: plotting with Python
StevenBlack/hosts                          3616
Extending and consolidating hosts files from a variety of sources like adaway.org, mvps.org, malwaredomains.com, someonewhocares.org, yoyo.org, and potentially others.  You can optionally invoke extensions to block additional sites by category.
django-debug-toolbar/django-debug-toolbar  3612
A configurable set of panels that display various debug information about the current request/response.
locustio/locust                            3609
Scalable user load testing tool written in Python
sivel/speedtest-cli                        3602
Command line interface for testing internet bandwidth using speedtest.net
samshadwell/TrumpScript                    3596
Make Python great again
karpathy/neuraltalk                        3576
NeuralTalk is a Python+numpy project for learning Multimodal Recurrent Neural Networks that describe images with sentences.
lauris/awesome-scala                       3534
A community driven list of useful Scala libraries, frameworks and software.
reverse-shell/routersploit                 3527
The Router Exploitation Framework
torchbox/wagtail                           3485
A Django content management system focused on flexibility and user experience
home-assistant/home-assistant              3482
:house_with_garden: Open-source home automation platform running on Python 3
google/yapf                                3464
A formatter for Python files
nltk/nltk                                  3448
NLTK Source
tangqiaoboy/iOSBlogCN                      3441
中文 iOS/Mac 开发博客列表
tgalal/yowsup                              3415
The python WhatsApp library
tweepy/tweepy                              3409
Twitter for Python!
audreyr/cookiecutter                       3394
A command-line utility that creates projects from cookiecutters (project templates). E.g. Python package projects, jQuery plugin projects.
larsenwork/monoid                          3390
Customisable coding font with alternates, ligatures and contextual positioning. Crazy crisp at 12px/9pt. http://larsenwork.com/monoid/
pallets/click                              3379
Python composable command line utility
amoffat/sh                                 3362
Python process launching
KeyboardFire/mkcast                        3331
[OBSOLETE - see readme] A tool for creating GIF screencasts of a terminal, with key presses overlaid.
pallets/jinja                              3326
The Jinja2 template engine
fastmonkeys/stellar                        3314
Fast database snapshot and restore tool for development
nicolaiarocci/eve                          3273
Simple REST APIs
quantopian/zipline                         3261
Zipline, a Pythonic Algorithmic Trading Library
codelucas/newspaper                        3253
News, full-text, and article metadata extraction in Python 3 
chrissimpkins/codeface                     3208
Typefaces for source code beautification
snare/voltron                              3203
A hacky debugger UI for hackers
newsapps/beeswithmachineguns               3203
A utility for arming (creating) many bees (micro EC2 instances) to attack (load test) targets (web applications).
idank/explainshell                         3184
match command-line arguments to their help text
timothycrosley/hug                         3141
Embrace the APIs of the future. Hug aims to make developing APIs as simple as possible, but no simpler.
midgetspy/Sick-Beard                       3134
PVR & episode guide that downloads and manages all your TV shows 
jisaacks/GitGutter                         3126
A Sublime Text 2/3 plugin to see git diff in gutter
jayfk/statuspage                           3112
A statuspage generator that lets you host your statuspage for free on Github.
jgm/CommonMark                             3071
CommonMark spec, with reference implementations in C and JavaScript
crsmithdev/arrow                           3063
Better dates & times for Python
benoitc/gunicorn                           3055
gunicorn 'Green Unicorn' is a WSGI HTTP Server for UNIX, fast clients and sleepy applications.
sloria/TextBlob                            3043
Simple, Pythonic, text processing--Sentiment analysis, part-of-speech tagging, noun phrase extraction, translation, and more.
mwaskom/seaborn                            3038
Statistical data visualization using matplotlib
reinderien/mimic                           3019
[ab]using Unicode to create tragedy
kennethreitz/osx-gcc-installer             3017
GCC Installer for OSX! Without Xcode!
klen/python-mode                           3013
Vim python-mode. PyLint, Rope, Pydoc, breakpoints from box.
nvie/rq                                    2996
Simple job queues for Python
django-tastypie/django-tastypie            2974
Creating delicious APIs for Django apps since 2010.
wbond/package_control                      2970
The Sublime Text package manager
fogleman/Minecraft                         2961
Simple Minecraft-inspired program using Python and Pyglet
facebook/augmented-traffic-control         2961
Augmented Traffic Control: A tool to simulate network conditions
nylas/sync-engine                          2946
:incoming_envelope: IMAP/SMTP sync system with modern APIs
jasperproject/jasper-client                2930
Client code for Jasper voice computing platform
falconry/falcon                            2920
Falcon is a low-level, high-performance Python framework for building HTTP APIs, app backends, and higher-level frameworks.
mopidy/mopidy                              2905
Mopidy is an extensible music server that plays music from local disk, Spotify, SoundCloud, Google Play Music, and more. You edit the playlist from any phone, tablet, or computer using a range of MPD and web clients.
sympy/sympy                                2893
A computer algebra system written in pure Python
Runscope/httpbin                           2881
HTTP Request & Response Service, written in Python + Flask.
facebook/PathPicker                        2879
PathPicker accepts a wide range of input -- output from git commands, grep results, searches -- pretty much anything.
After parsing the input, PathPicker presents you with a nice UI to select which files you're interested in. After that you can open them in your favorite editor or execute arbitrary commands.
donnemartin/saws                           2873
A supercharged AWS command line interface (CLI).
donnemartin/gitsome                        2854
A supercharged Git/GitHub command line interface (CLI).
avinassh/rockstar                          2847
Makes you a Rockstar C++ Programmer in 2 minutes
coleifer/peewee                            2844
a small, expressive orm -- supports postgresql, mysql and sqlite
pypa/pip                                   2843
The PyPA recommended tool for installing Python packages
apache/incubator-airflow                   2836
Apache Airflow (Incubating)
taigaio/taiga-back                         2825
Project management web application with scrum in mind! Built on top of Django and AngularJS (Backend Code)
kstenerud/iOS-Universal-Framework          2783
An XCode project template to build universal frameworks (arm7, arm7s, and simulator) for iOS / iPhone.
gevent/gevent                              2770
Coroutine-based concurrency library for Python
chrippa/livestreamer                       2768
Command-line utility that extracts streams from various services and pipes them into a video player of choice.
tflearn/tflearn                            2765
Deep learning library featuring a higher-level API for TensorFlow.
Kinto/kinto                                2760
A minimalist JSON storage service with synchronisation and sharing abilities.
tqdm/tqdm                                  2750
A fast, extensible progress bar for Python
koenbok/Cactus                             2744
Static site generator for designers. Uses Python and Django templates.
JuanPotato/Legofy                          2741
Make images look as if they are made out of 1x1 LEGO blocks
django-extensions/django-extensions        2736
This is a repository for collecting global custom management extensions for the Django Framework. 
Katee/quietnet                             2712
Simple chat program using inaudible sounds and a computer's microphone and speaker.
dbcli/mycli                                2711
A Terminal Client for MySQL with AutoCompletion and Syntax Highlighting.
10se1ucgo/DisableWinTracking               2707
Uses some known methods that attempt to disable tracking in Windows 10
pavelgonchar/colornet                      2701
Neural Network to colorize grayscale images
stephenmcd/mezzanine                       2694
CMS framework for Django
rtfd/readthedocs.org                       2681
source code to readthedocs.org
mahmoud/boltons                            2654
Like builtins, but boltons. Constructs/recipes/snippets that would be handy in the standard library. Nothing like Michael Bolton. 
taobao/nginx-book                          2642
Nginx开发从入门到精通
ryanoasis/nerd-fonts                       2640
:abcd: Collection of over 25 patched fonts (over 5,700 variations) & FontForge font patcher python script for Powerline, Font Awesome, Octicons, Devicons, and Vim Devicons. Includes: Droid Sans, Meslo, Source Code, AnonymousPro, Hack, ProFont, Inconsolata, and many more
pallets/werkzeug                           2627
A flexible WSGI implementation and toolkit
paramiko/paramiko                          2610
Native Python SSHv2 protocol library
edx/edx-platform                           2598
The Open edX platform, the software that powers edX!
mkdocs/mkdocs                              2592
Project documentation with Markdown.
docker/docker-registry                     2589
This is **DEPRECATED**! Please go to https://github.com/docker/distribution
piskvorky/gensim                           2584
Topic Modelling for Humans
arachnys/cabot                             2573
Self-hosted, easily-deployable monitoring and alerts service - like a lightweight PagerDuty
cyrus-and/gdb-dashboard                    2566
Modular visual interface for GDB in Python
jonathanslenders/python-prompt-toolkit     2563
Library for building powerful interactive command lines in Python
redecentralize/alternative-internet        2557
A collection of interesting new networks and tech aiming at decentralisation (in some form).
Supervisor/supervisor                      2534
Supervisor process control system for UNIX
gelstudios/gitfiti                         2533
abusing github commit history for the lulz
yhat/ggplot                                2529
ggplot for python
python-pillow/Pillow                       2523
The friendly PIL fork (Python Imaging Library)
rushter/data-science-blogs                 2516
A curated list of data science blogs
milkbikis/powerline-shell                  2515
A beautiful and useful prompt for your shell
CouchPotato/CouchPotatoServer              2512
Automatic Movie Downloading via NZBs & Torrents
Russell91/pythonpy                         2502
the swiss army knife of the command line
gregmalcolm/python_koans                   2492
Python Koans - Learn Python through TDD
donnemartin/interactive-coding-challenges  2489
Continually updated, interactive, test-driven Python coding challenges (algorithms and data structures) typically found in coding interviews.
jorgebastida/glue                          2483
Glue is a simple command line tool to generate CSS sprites
nvdv/vprof                                 2482
Visual Python profiler
diafygi/acme-tiny                          2469
A tiny script to issue and renew TLS certs from Let's Encrypt
awentzonline/image-analogies               2466
Generate image analogies using neural matching and blending.
MobileChromeApps/mobile-chrome-apps        2461
Chrome apps on Android and iOS
tensorflow/skflow                          2449
Simplified interface for TensorFlow (mimicking Scikit Learn) for Deep Learning
spadgos/sublime-jsdocs                     2441
Simplifies writing DocBlock comments in Javascript, PHP, CoffeeScript, Actionscript, C & C++
seatgeek/fuzzywuzzy                        2440
Fuzzy String Matching in Python
somerandomdude/Iconic                      2428
A minimal set of icons in raster, vector and font formats — free for public use.
kemayo/sublime-text-git                    2423
Plugin for some git integration into sublime text
joestump/python-oauth2                     2407
A fully tested, abstract interface to creating OAuth clients and servers.
what-studio/profiling                      2400
An interactive continuous Python profiler.
sokolovstas/SublimeWebInspector            2398
Web Inspector allow you debug Javascript right in the editor
SirVer/ultisnips                           2388
UltiSnips - The ultimate snippet solution for Vim. Send pull requests to SirVer/ultisnips!
jmcarp/robobrowser                         2383
maraujop/django-crispy-forms               2379
The best way to have DRY Django forms. The app provides a tag and filter that lets you quickly render forms in a div format while providing an enormous amount of capability to configure and control the rendered HTML.
emre/storm                                 2375
Manage your SSH like a boss.
pennersr/django-allauth                    2371
Integrated set of Django applications addressing authentication, registration, account management as well as 3rd party (social) account authentication.
CiscoCloud/mantl                           2367
Mantl is a modern platform for rapidly deploying globally distributed services
scipy/scipy                                2353
Scipy library main repository
chrisallenlane/cheat                       2342
cheat allows you to create and view interactive cheatsheets on the command-line. It was designed to help remind *nix system administrators of options for commands that they use frequently, but not frequently enough to remember.
jeanphix/Ghost.py                          2329
Webkit based scriptable web browser for python. 
ClusterHQ/flocker                          2328
Container data volume manager for your Dockerized application
omab/django-social-auth                    2313
Django social authentication made simple
openai/gym                                 2312
A toolkit for developing and comparing reinforcement learning algorithms.
aziz/PlainTasks                            2311
An opinionated todo-list plugin for Sublime Text editor (version 2 and 3)
omab/python-social-auth                    2293
Social auth made simple
google/roboto                              2292
The Roboto family of fonts
lg/murder                                  2288
Large scale server deploys using BitTorrent and the BitTornado library
kennethreitz/records                       2267
SQL for Humans™
kivy/python-for-android                    2262
Turn your Python application into an Android APK - build your own python and extensions
pudo/dataset                               2239
Easy-to-use data handling for SQL data stores with support for implicit table creation, bulk loading, and transactions. Dataset also includes support for freezing data to CSV and JSON flat files.
nodejs/node-gyp                            2238
Node.js native addon build tool
thearn/webcam-pulse-detector               2234
A python application that detects and highlights the heart-rate of an individual (using only their own webcam) in real-time.
realpython/discover-flask                  2228
Full Stack Web Development with Flask.
jeffknupp/sandman                          2222
Sandman "makes things REST".
dbader/schedule                            2198
Python job scheduling for humans.
buildbot/buildbot                          2170
Python-based continuous integration testing framework; your pull requests are more than welcome!
livid/v2ex                                 2160
Community running on Google App Engine
awslabs/aws-shell                          2160
An integrated shell for working with the AWS CLI.
AppScale/appscale                          2152
The Open Source Implementation of Google App Engine -- Take your apps everywhere.
wireservice/csvkit                         2150
A suite of utilities for converting to and working with CSV, the king of tabular file formats.
networkx/networkx                          2140
Official NetworkX source code repository.  
Lasagne/Lasagne                            2136
Lightweight library to build and train neural networks in Theano
tschellenbach/Stream-Framework             2131
Stream Framework is a Python library, which allows you to build newsfeed and notification systems using Cassandra and/or Redis.
davidhalter/jedi                           2105
Awesome autocompletion and static analysis library for python.
worldveil/dejavu                           2096
Audio fingerprinting and recognition in Python
Zulko/moviepy                              2093
Video editing with Python
lisa-lab/pylearn2                          2093
A Machine Learning library based on Theano
mnielsen/neural-networks-and-deep-learning 2088
Code samples for my book "Neural Networks and Deep Learning"
spinnaker/spinnaker                        2085
Spinnaker is an open source, multi-cloud continuous delivery platform for releasing software changes with high velocity and confidence.
ajalt/fuckitpy                             2066
The Python error steamroller.
gorakhargosh/watchdog                      2059
Python library and shell utilities to monitor filesystem events.
mooz/percol                                2055
adds flavor of interactive filtering to the traditional pipe concept of UNIX shell
JakeWharton/pidcat                         2043
Colored logcat script which only shows log entries for a specific application package.
django-oscar/django-oscar                  2015
Domain-driven e-commerce for Django
martinblech/xmltodict                      2013
Python module that makes working with XML feel like you are working with JSON
flask-restful/flask-restful                2013
Simple framework for creating REST APIs
kennethreitz/clint                         2011
Python Command-line Application Tools
Pylons/pyramid                             2003
Pyramid web framework
kovidgoyal/calibre                         1993
The official source code repository for the calibre ebook manager
django-haystack/django-haystack            1979
Modular search for Django
nlintz/TensorFlow-Tutorials                1977
Simple tutorials using Google's TensorFlow Framework
rembo10/headphones                         1975
Automatic music downloader for SABnzbd
maebert/jrnl                               1970
A simple command line journal application that stores your journal in a plain text file.
donnemartin/dev-setup                      1966
Mac OS X development environment setup:  Easy-to-understand instructions with automated setup scripts for developer tools like Vim, Sublime Text, Bash, iTerm, Python data analysis, Spark, Hadoop MapReduce, AWS, Heroku, JavaScript web development, Android development, common data stores, and dev-based OS X defaults.
lisa-lab/DeepLearningTutorials             1965
Deep Learning Tutorial notes and code. See the wiki for more info.
devstructure/blueprint                     1957
Reverse engineer server configuration
kennethreitz/tablib                        1944
Python Module for Tabular Datasets in XLS, CSV, JSON, YAML, &c.
Yelp/elastalert                            1943
Easy & Flexible Alerting With ElasticSearch
lihaoyi/macropy                            1940
Macros in Python: quasiquotes, case classes, LINQ and more!
kachayev/fn.py                             1937
Functional programming in Python: implementation of missing features to enjoy FP
jeffkaufman/icdiff                         1935
improved colored diff
donnemartin/awesome-aws                    1917
A curated list of awesome Amazon Web Services (AWS) libraries, open source repos, guides, blogs, and other resources.  Featuring the Fiery Meter of AWSome.
NervanaSystems/neon                        1911
Fast, scalable, easy-to-use Python based Deep Learning Framework by Nervana™
donnemartin/haxor-news                     1905
Browse Hacker News like a haxor: A Hacker News command line interface (CLI).
KeepSafe/aiohttp                           1884
http client/server for asyncio (PEP-3156)
fivesheep/chnroutes                        1882
scripts help chinese netizen, who uses vpn to combat censorship, by modifying the route table so as routing only the censored ip to the vpn
Tribler/tribler                            1878
Privacy enhanced BitTorrent client with P2P content discovery
google/nogotofail                          1874
An on-path blackbox network traffic security testing tool
wrobstory/vincent                          1873
A Python to Vega translator
s3tools/s3cmd                              1861
Official s3cmd repo -- Command line tool for managing Amazon S3 and CloudFront services
iambus/xunlei-lixian                       1841
迅雷离线下载脚本
houtianze/bypy                             1835
Python client for Baidu Yun (Personal Cloud Storage) 百度云/百度网盘Python客户端
numba/numba                                1833
NumPy aware dynamic Python compiler using LLVM
jonathanslenders/pyvim                     1833
Pure Python Vim clone.
PeterDing/iScript                          1830
各种脚本 -- 关于 虾米 xiami.com, 百度网盘 pan.baidu.com, 115网盘 115.com, 网易音乐 music.163.com, 百度音乐 music.baidu.com, 360网盘/云盘 yunpan.cn, 视频解析 flvxz.com, bt torrent ↔ magnet, ed2k 搜索, tumblr 图片下载, unzip
jokkedk/webgrind                           1829
Xdebug Profiling Web Frontend in PHP
honza/vim-snippets                         1827
vim-snipmate default snippets (Previously snipmate-snippets)
lektor/lektor                              1824
The lektor static file content management system
gongjianhui/AppleDNS                       1818
Apple 网络服务加速配置。真的快,快出声!(少数派、Appinn、Mac玩儿法 推荐)
Yelp/mrjob                                 1809
Run MapReduce jobs on Hadoop or Amazon Web Services
pyinstaller/pyinstaller                    1808
PyInstaller official GIT repository 
pybrain/pybrain                            1807
joelpx/plasma                              1802
Interactive disassembler for x86/ARM/MIPS. Generates indented pseudo-code with colored syntax code.
revolunet/sublimetext-markdown-preview     1801
markdown preview and build plugin for sublime text 2/3
cloudera/hue                               1794
Let’s Big Data. Hue is an open source Web interface for analyzing data with Hadoop and Spark.
openstack/nova                             1787
OpenStack Compute (Nova)
anishathalye/git-remote-dropbox            1778
A transparent bridge between Git and Dropbox - use a Dropbox (shared) folder as a Git remote! :gift: http://www.anishathalye.com/2015/08/19/git-remote-dropbox/
python/cpython                             1777
Semi-official read-only mirror of the CPython Mercurial repository
douban/dpark                               1769
Python clone of Spark,  a MapReduce alike framework in Python
darknessomi/musicbox                       1767
网易云音乐命令行版本
getredash/redash                           1762
Make Your Company Data Driven. Connect to any data source, easily visualize and share your data.
cuckoosandbox/cuckoo                       1744
Cuckoo Sandbox is an automated dynamic malware analysis system
amscanne/huptime                           1744
Utility for zero downtime restarts of unmodified programs.
Jahaja/psdash                              1743
A linux system information web dashboard using psutils and flask
PyMySQL/PyMySQL                            1734
Pure Python MySQL Client
flask-admin/flask-admin                    1731
Simple and extensible administrative interface framework for Flask
djaiss/mapsicon                            1724
A free collection of maps for every country in the world, available in 11 sizes or in SVG.
etsy/skyline                               1724
It'll detect your anomalies! Part of the Kale stack.
mher/flower                                1724
Real-time monitor and web admin for Celery distributed task queue
mongodb/mongo-python-driver                1717
PyMongo - the Python driver for MongoDB
Bitmessage/PyBitmessage                    1716
noamraph/tqdm                              1714
Add a progress meter to your loops in a second
freedomofpress/securedrop                  1712
GitHub repository for the SecureDrop whistleblower platform. Do not submit tips here!
python-visualization/folium                1712
Python Data. Leaflet.js Maps. 
jflesch/paperwork                          1709
:paperclip: Using scanners and OCR to grep paper documents the easy way (Linux only)
etsy/logster                               1705
Parse log files, generate metrics for Graphite and Ganglia
0rpc/zerorpc-python                        1702
zerorpc for python
samuraisam/pyapns                          1698
An APNS provider with multi-app support.
DTVD/rainbowstream                         1697
A smart and nice Twitter client on terminal written in Python.
mps-youtube/mps-youtube                    1694
Terminal based YouTube player and downloader
burnash/gspread                            1693
Google Spreadsheets Python API
PyCQA/pycodestyle                          1691
Simple Python style checker in one Python file
iBaa/PlexConnect                           1689
Plex @ aTV - think different...
kennethreitz/envoy                         1688
Python Subprocesses for Humans™.
feross/SpoofMAC                            1687
:briefcase: Change your MAC address for debugging
pypa/virtualenv                            1687
Virtual Python Environment builder
devttys0/binwalk                           1684
Firmware Analysis Tool
django-compressor/django-compressor        1676
Compresses linked and inline javascript or CSS into a single cached file.
ujjwalkarn/DataSciencePython               1676
common data analysis and machine learning tasks using python
mobolic/facebook-sdk                       1673
Facebook Platform Python SDK
DanMcInerney/wifijammer                    1672
Continuously jam all wifi clients/routers
cython/cython                              1670
A Python to C compiler
stamparm/maltrail                          1659
Malicious traffic detection system
wuub/SublimeREPL                           1658
SublimeREPL - run an interpreter inside ST2 (Clojure, CoffeeScript, F#, Groovy, Haskell, Lua, MozRepl, NodeJS, Python, R, Ruby, Scala, shell or configure one yourself)
emirozer/fake2db                           1653
create custom test databases that are populated with fake data
viewfinderco/viewfinder                    1634
Viewfinder client and server code
simon-weber/gmusicapi                      1634
An unofficial client library for Google Music.
ironmaniiith/Github-profile-name-writer    1628
:sunglasses: Write your name using the github commits and make your profile awesome
giampaolo/psutil                           1625
A cross-platform process and system utilities module for Python
AlessandroZ/LaZagne                        1621
Credentials recovery project
sixohsix/twitter                           1617
Python Twitter API
sshwsfc/xadmin                             1615
Drop-in replacement of Django admin comes with lots of goodies, fully extensible with plugin support, pretty UI based on Twitter Bootstrap.
yenchenlin/DeepLearningFlappyBird          1611
Flappy Bird hack using Deep Reinforcement Learning (Deep Q-learning).
jsvine/waybackpack                         1608
Download the entire Wayback Machine archive for a given URL.
nvie/pip-tools                             1607
A set of tools to keep your pinned Python dependencies fresh.
VitaliyRodnenko/geeknote                   1601
Console client for Evernote.
titoBouzout/SideBarEnhancements            1596
Enhancements to Sublime Text sidebar. Files and folders.
hephaest0s/usbkill                         1591
« usbkill » is an anti-forensic kill-switch that waits for a change on your USB ports and then immediately shuts down your computer.
asciimoo/drawille                          1577
Pixel graphics in terminal with unicode braille characters
etianen/django-reversion                   1574
django-reversion is an extension to the Django web framework that provides version control for model instances.
pydanny/cookiecutter-django                1571
Cookiecutter Django is a framework for jumpstarting production-ready Django projects quickly.
graphific/DeepDreamVideo                   1569
implementing deep dream on video
schematics/schematics                      1566
Python Data Structures for Humans™.
sightmachine/SimpleCV                      1563
The Open Source Framework for Machine Vision
posativ/isso                               1562
a Disqus alternative
miguelgrinberg/flasky                      1561
Companion code to my O'Reilly book "Flask Web Development".
gnemoug/distribute_crawler                 1557
使用scrapy,redis, mongodb,graphite实现的一个分布式网络爬虫,底层存储mongodb集群,分布式使用redis实现,爬虫状态显示使用graphite实现
gurgeh/selfspy                             1557
Log everything you do on the computer, for statistics, future reference and all-around fun!
pixie-lang/pixie                           1555
A small, fast, native lisp with "magical" powers
dae/anki                                   1554
Anki for desktop computers
MagicStack/uvloop                          1550
Ultra fast implementation of asyncio event loop on top of libuv.
sripathikrishnan/redis-rdb-tools           1540
Parse Redis dump.rdb files, Analyze Memory, and Export Data to JSON
euske/pdfminer                             1532
Python PDF Parser
DanMcInerney/LANs.py                       1530
Inject code, jam wifi, and spy on wifi users
brennerm/PyTricks                          1528
Collection of less popular features and tricks for the Python programming language
playframework/play1                        1525
Play framework
treeio/treeio                              1524
Tree.io
micahflee/onionshare                       1516
Securely and anonymously share a file of any size
hut/ranger                                 1505
An VIM-inspired filemanager for the console
pymc-devs/pymc3                            1493
Probabilistic Programming in Python. Uses Theano as a backend, supports NUTS and ADVI.
blaze/blaze                                1486
NumPy and Pandas interface to Big Data
jaredks/rumps                              1477
Ridiculously Uncomplicated Mac os x Python Statusbar apps
python/mypy                                1475
Optional static typing for Python
nryoung/algorithms                         1474
An educational library of algorithms in Python
SiCKRAGETV/SiCKRAGE                        1474
SickRage - Searches TheTVDB for shows
Flolagale/mailin                           1474
Artisanal inbound emails for every web app
statsmodels/statsmodels                    1474
Statsmodels: statistical modeling and econometrics in Python
stitchfix/pyxley                           1473
Python helpers for building dashboards using Flask and React
docker/docker-py                           1469
An API client for docker written in Python
mmin18/LayoutCast                          1466
Cast android code and resource changes to the running application through ADB.
alex/django-taggit                         1460
Simple tagging for django
fail2ban/fail2ban                          1458
Daemon to ban hosts that cause multiple authentication errors
overviewer/Minecraft-Overviewer            1449
Render high-resolution maps of a Minecraft world with a Google Maps powered interface
mhagger/git-imerge                         1442
Incremental merge for git
zerodb/zerodb                              1439
ZeroDB is an end-to-end encrypted database. Data can be stored and queried on untrusted database servers without ever exposing the encryption key. Clients can execute remote queries against the encrypted data without downloading all of it or suffering an excessive performance hit.
waditu/tushare                             1435
TuShare is a utility for crawling historical data of China stocks
kennethreitz/grequests                     1431
Requests + Gevent = <3
wal-e/wal-e                                1427
Simple Continuous Archiving for Postgres
carltongibson/django-filter                1425
A generic system for filtering Django QuerySets based on user selections
eastlakeside/interpy-zh                    1423
《Python进阶》(Intermediate Python 中文版)
litl/rauth                                 1423
A Python library for OAuth 1.0/a, 2.0, and Ofly.
facebookarchive/python-instagram           1420
Python Client for Instagram API
hylang/hy                                  1415
A dialect of Lisp that's embedded in Python
pfnet/chainer                              1415
A flexible framework of neural networks for deep learning
utahta/pythonbrew                          1414
Python Environment manager
Gallopsled/pwntools                        1414
CTF framework used by Gallopsled in every CTF
huhamhire/huhamhire-hosts                  1411
hosts for Internet Freedom
ryankiros/neural-storyteller               1410
A recurrent neural network for generating little stories about images
prakhar1989/Algorithms                     1408
:computer: Data Structures and Algorithms in Python
rstacruz/sparkup                           1407
A parser for a condensed HTML format
jiaaro/pydub                               1401
Manipulate audio with a simple and easy high level interface
luispedro/BuildingMachineLearningSystemsWithPython 1399
Source Code for the book Building Machine Learning Systems with Python
apprenticeharper/DeDRM_tools               1399
DeDRM tools for ebooks
mininet/mininet                            1394
Emulator for rapid prototyping of Software Defined Networks
dyve/django-bootstrap3                     1392
Bootstrap 3 integration with Django.
fraser-hemp/gradify                        1392
CSS gradient placeholders
StackStorm/st2                             1389
StackStorm (aka "IFTTT for Ops") is event-driven automation commonly used for auto-remediation, security responses, facilitated troubleshooting, complex deployments, and more. Includes rules engine, workflow,1800+ integrations (see /st2contrib), native ChatOps and so forth.  Installer available at http://docs.stackstorm.com/install/index.html. Ping us on slack - https://stackstorm-community.slack.com/. 
hhatto/autopep8                            1385
A tool that automatically formats Python code to conform to the PEP 8 style guide.
bitcoinbook/bitcoinbook                    1384
Mastering Bitcoin - Unlocking digital currencies
google/enjarify                            1361
trustedsec/social-engineer-toolkit         1361
The Social-Engineer Toolkit (SET) repository from TrustedSec - All new versions of SET will be deployed here.
google/pyringe                             1357
Debugger capable of attaching to and injecting code into python processes.
hickford/MechanicalSoup                    1354
A Python library for automating interaction with websites.
i-tu/Hasklig                               1346
Hasklig - a code font with monospaced ligatures
twilio/stashboard                          1342
An open-source status dashboard running on App Engine
divmain/GitSavvy                           1340
Full git and GitHub integration with Sublime Text 3.
n1nj4sec/pupy                              1340
Pupy is an opensource, multi-platform (Windows, Linux, OSX, Android), multi function RAT (Remote Administration Tool) mainly written in python. It features a all-in-memory execution guideline and leaves very low footprint. Pupy can communicate using various transports, migrate into processes (reflective injection), load remote python code, python packages and python C-extensions from memory.
guillermooo/Vintageous                     1338
Vi/Vim emulation for Sublime Text 3
aaronsw/html2text                          1337
Convert HTML to Markdown-formatted text.
isnowfy/snownlp                            1337
Python library for processing Chinese text
zeromq/pyzmq                               1329
PyZMQ:  Python bindings for zeromq
openstack/swift                            1326
OpenStack Object Storage (Swift)
jonathanslenders/ptpython                  1321
A better Python REPL
soumith/convnet-benchmarks                 1319
Easy benchmarking of all publicly accessible implementations of convnets
programthink/zhao                          1316
【编程随想】整理的《太子党关系网络》,专门揭露赵国的权贵
Kozea/pygal                                1316
PYthon svg GrAph plotting Library
facelessuser/BracketHighlighter            1316
Bracket and tag highlighter for Sublime Text
MongoEngine/mongoengine                    1312
A Python Object-Document-Mapper for working with MongoDB
sublimehq/anim_encoder                     1312
andelf/fuck12306                           1308
12306 图片验证码识别测试
zzzeek/sqlalchemy                          1306
See the development link for contribution guidelines
dz0ny/leapcast                             1304
ChromeCast emulation app for any device
amoffat/snake                              1299
Full Python Scripting in Vim
bitly/data_hacks                           1297
Command line utilities for data analysis
mshang/python-elevator-challenge           1295
So You Think You Can Program An Elevator
rolando/scrapy-redis                       1294
Redis-based components for scrapy that allows distributed crawling
arc90/git-sweep                            1293
A command-line tool that helps you clean up Git branches that have been merged into master.
antiboredom/videogrep                      1291
automatic video supercuts with python
Suor/funcy                                 1289
A fancy and practical functional tools
hyde/hyde                                  1286
A Python Static Website Generator
rochacbruno/quokka                         1282
CMS (Content Management System) - Python, Flask and MongoDB
yasoob/intermediatePython                  1277
HypothesisWorks/hypothesis-python          1270
Advanced property-based (QuickCheck-like) testing for Python
charlierguo/gmail                          1265
A Pythonic interface for Google Mail
LiuLang/bcloud                             1259
百度网盘的linux桌面客户端
quantmind/pulsar                           1257
Event driven framework for python
django-mptt/django-mptt                    1256
Utilities for implementing a modified pre-order traversal tree in django.
twisted/twisted                            1255
Event-driven networking engine written in Python.
BrightcoveOS/Diamond                       1254
sindresorhus/editorconfig-sublime          1253
Helps developers maintain consistent coding styles between different editors - Sublime Text plugin
egrcc/zhihu-python                         1253
获取知乎内容信息,包括问题,答案,用户,收藏夹信息
bear/python-twitter                        1252
A Python wrapper around the Twitter API.
mitsuhiko/flask-sqlalchemy                 1252
Adds SQLAlchemy support to Flask
gaubert/gmvault                            1250
gmail backup software
alex-sherman/deco                          1249
derv82/wifite                              1245
frappe/erpnext                             1243
Open Source ERP built for the Web. Uses Python, MariaDB.
lorien/grab                                1242
Web Scraping Framework
Robot-Will/Stino                           1242
A Sublime Text Plugin for Arduino
hzlzh/AlfredWorkflow.com                   1241
A public Collection of Alfred Workflows.
google/grr                                 1240
GRR Rapid Response: remote live forensics for incident response
amueller/word_cloud                        1240
A little word cloud generator in Python
Rip-Rip/clang_complete                     1238
Vim plugin that use clang for completing C/C++ code.
byt3bl33d3r/MITMf                          1235
Framework for Man-In-The-Middle attacks
getsentry/responses                        1234
A utility for mocking out the Python Requests library.
qiwsir/StarterLearningPython               1227
Learning Python: from Beginner to Master. http://www.itdiffer.com
yidao620c/python3-cookbook                 1226
《Python Cookbook》 3rd Edition Translation
ckan/ckan                                  1222
CKAN is an open-source DMS (data management system) for powering data hubs and data portals. CKAN makes it easy to publish, share and use data. It powers datahub.io, catalog.data.gov and data.gov.uk among many other sites.
daviddrysdale/python-phonenumbers          1222
Python port of Google's libphonenumber
kennethreitz/inbox.py                      1220
Python SMTP Server for Humans
borgbackup/borg                            1220
Deduplicating backup program with compression and authenticated encryption.
cloudtools/troposphere                     1211
troposphere - Python library to create AWS CloudFormation descriptions
elvanderb/TCP-32764                        1210
some codes and notes about the backdoor listening on TCP-32764 in linksys WAG200G.
thampiman/reverse-geocoder                 1210
A fast, offline reverse geocoder in Python
SublimeText/LaTeXTools                     1206
LaTeX plugin for Sublime Text 2 and 3
bslatkin/dpxdt                             1203
Make continuous deployment safe by comparing before and after webpage screenshots for each release. Depicted shows when any visual, perceptual differences are found. This is the ultimate, automated end-to-end test.
tomerfiliba/plumbum                        1202
Plumbum: Shell Combinators
gabrielfalcao/HTTPretty                    1202
HTTP client mocking tool for Python, it's like ruby's FakeWeb for python
Fantomas42/django-blog-zinnia              1196
Simple yet powerful and really extendable application for managing a blog within your Django Web site.
The-Compiler/qutebrowser                   1194
A keyboard-driven, vim-like browser based on PyQt5.
pyinvoke/invoke                            1193
Simple Python task execution
whtsky/WeRoBot                             1192
WeRoBot是一个微信机器人框架
tschellenbach/Django-facebook              1192
Facebook open graph api implementation using the Django web framework in python
NVIDIA/DIGITS                              1180
Deep Learning GPU Training System
ryanmcgrath/twython                        1179
Actively maintained, pure Python wrapper for the Twitter API. Supports both normal and streaming Twitter APIs.
imwilsonxu/fbone                           1178
Fbone (Flask bone) is a Flask (Python microframework) template/bootstrap/boilerplate application.
LuminosoInsight/python-ftfy                1177
Given Unicode text, make its representation consistent and possibly less broken.
sebastien/cuisine                          1176
Chef-like functionality for Fabric
ternjs/tern_for_vim                        1175
Tern plugin for Vim
myusuf3/delorean                           1175
Delorean: Time Travel Made Easy
secretsquirrel/the-backdoor-factory        1173
Patch PE, ELF, Mach-O binaries with shellcode
seb-m/pyinotify                            1171
Monitoring filesystems events with inotify on Linux.
Guake/guake                                1168
Drop-down terminal for GNOME
kragniz/json-sempai                        1167
Use JSON files as if they are python modules
scopatz/xonsh                              1161
xonsh is a Python-ish, BASHwards-facing shell.
munificent/vigil                           1158
Vigil, the eternal morally vigilant programming language
kbengine/kbengine                          1154
A MMOG engine of server.
xhtml2pdf/xhtml2pdf                        1145
HTML/CSS to PDF converter based on Python
dcramer/django-devserver                   1143
A drop-in replacement for Django's runserver.
dlitz/pycrypto                             1143
The Python Cryptography Toolkit
jdc0589/JsFormat                           1141
Javascript formatting for Sublime Text 2 & 3
hannes-brt/hebel                           1140
GPU-Accelerated Deep Learning Library in Python
joelgrus/data-science-from-scratch         1139
code for Data Science From Scratch book
redodo/tortilla                            1137
Wrapping web APIs made easy.
idan/oauthlib                              1135
A generic, spec-compliant, thorough implementation of the OAuth request-signing logic
madisonmay/Tomorrow                        1134
Magic decorator syntax for asynchronous code in Python
botherder/detekt                           1134
Malware triaging tool
elastic/curator                            1132
Curator: Tending your Elasticsearch indices
cemoody/lda2vec                            1131
crossbario/autobahn-python                 1131
WebSocket and WAMP in Python for Twisted and asyncio
marshmallow-code/marshmallow               1131
A lightweight library for converting complex objects to and from simple Python datatypes.
oliver006/elasticsearch-gmail              1130
Index your Gmail Inbox with Elasticsearch
web2py/web2py                              1130
Free and open source full-stack enterprise framework for agile development of secure database-driven web-based applications, written and programmable in Python.
goldsmith/Wikipedia                        1130
A Pythonic wrapper for the Wikipedia API
cobbler/cobbler                            1130
everyone's favorite Linux Install & Update Server
kevinburke/hamms                           1129
Malformed servers to test your HTTP client
mewwts/addict                              1128
The Python Dict that's better than heroin.
paulhammond/webkit2png                     1126
png screenshots of webpages
django-guardian/django-guardian            1126
Per object permissions for Django
dahlia/awesome-sqlalchemy                  1125
A curated list of awesome tools for SQLAlchemy
ctfs/write-ups-2014                        1121
Wiki-like CTF write-ups repository, maintained by the community. 2014
khamidou/kite                              1120
(Obsolete, use https://github.com/inboxapp/inbox instead) A modern webmail.
cobrateam/splinter                         1115
splinter - python test framework for web applications 
mikedewar/d3py                             1110
a plottling library for python, based on D3
pytoolz/toolz                              1110
A functional standard library for Python.
nathanborror/django-basic-apps             1107
Simple prebuilt applications.
IDSIA/brainstorm                           1105
Fast, flexible and fun neural networks.
oldj/SwitchHosts                           1104
Switch hosts quickly!
jisungk/deepjazz                           1102
Deep learning driven jazz generation using Keras & Theano!
scikit-image/scikit-image                  1100
Image Processing SciKit (Toolbox for SciPy)
boto/boto3                                 1099
AWS SDK for Python
jupyterhub/jupyterhub                      1099
Multi-user server for Jupyter notebooks
spyder-ide/spyder                          1098
Official repository for Spyder - The Scientific PYthon Development EnviRonment
geopy/geopy                                1090
Geocoding library for Python.
andrewgodwin/channels                      1090
Developer-friendly asynchrony for Django
hackappcom/ibrute                          1088
AppleID bruteforce p0c
trentm/python-markdown2                    1087
markdown2: A fast and complete implementation of Markdown in Python
nvbn/everpad                               1087
Evernote client well integrated with linux desktop
bread-and-pepper/django-userena            1083
Accounts for Django made beautifully simple
jacobian-archive/djangobook.com            1081
longld/peda                                1076
PEDA - Python Exploit Development Assistance for GDB
seatgeek/sixpack                           1075
Sixpack is a language-agnostic a/b-testing framework
brack3t/django-braces                      1075
Reusable, generic mixins for Django
olgabot/prettyplotlib                      1073
Painlessly create beautiful matplotlib plots.
DamnWidget/anaconda                        1073
Anaconda turns your Sublime Text 3 in a full featured Python development IDE including autocompletion, code linting, IDE features, autopep8 formating, McCabe complexity checker and Vagrant for Sublime Text 3 using Jedi, PyFlakes, pep8, PyLint, pep257 and McCabe that will never freeze your Sublime Text 3
pyca/cryptography                          1072
cryptography is a package designed to expose cryptographic primitives and recipes to Python developers.
Newmu/dcgan_code                           1071
Deep Convolutional Generative Adversarial Networks
SublimeLinter/SublimeLinter3               1066
Interactive code linting framework for Sublime Text 3
jceb/vim-orgmode                           1065
Text outlining and task management for Vim based on Emacs' Org-Mode
defaultnamehere/zzzzz                      1061
Roleplay as the NSA by making creepy graphs of your friends
platformio/platformio                      1060
An open source ecosystem for IoT development :alien: Cross-platform build system and library manager. Continuous and IDE integration. Arduino, ESP8266 and ARM mbed compatible. Ready for Cloud compiling.
traverseda/pycraft                         1059
A fork of "Minecraft in 500 lines of python" intended to be used as a real engine, instead of as a learning example.
angusshire/greenhat                        1057
:construction_worker: Quick hack for making real work happen.
awesto/django-shop                         1056
A Django based shop system
plotly/plotly.py                           1054
the browser-based graphing library for python
amonapp/amonone                            1053
Amon One
mattupstate/overholt                       1051
Example Flask application illustrating some of my common practices
shazow/urllib3                             1049
Python HTTP library with thread-safe connection pooling, file post support, sanity friendly, and more.
dfm/osrc                                   1046
The Open Source Report Card
gmate/gmate                                1045
Set of plugins and improvements to make Gedit a powerfull programmer text editor
vispy/vispy                                1045
Main repository for Vispy
tdryer/hangups                             1042
the first third-party instant messaging client for Google Hangouts
gitpython-developers/GitPython             1041
GitPython is a python library used to interact with Git repositories.
rpicard/explore-flask                      1038
Source of Explore Flask book
adobe/brackets-shell                       1037
CEF3-based application shell for Brackets.
mathics/Mathics                            1036
a general-purpose computer algebra system
jazzband/django-pipeline                   1032
Pipeline is an asset packaging library for Django.
kanaka/websockify                          1031
Websockify is a WebSocket to TCP proxy/bridge. This allows a browser to connect  to any application/server/service. Implementations in Python, C, Node.js and Ruby.
Dobiasd/articles                           1030
thoughts on programming
qtile/qtile                                1028
:cookie: A small, flexible, scriptable tiling window manager written in Python
dabeaz/curio                               1027
Curio - The coroutine concurrency library.
CacheBrowser/cachebrowser                  1025
A proxy-less censorship resistance tool
facebookarchive/redis-faina                1023
A query analyzer that parses Redis' MONITOR command for counter/timing stats about query patterns
vimeo/graph-explorer                       1018
A graphite dashboard powered by structured metrics
PressLabs/gitfs                            1017
Version controlled file system
rhiever/tpot                               1016
A Python tool that automatically creates and optimizes machine learning pipelines using genetic programming.
maxcountryman/flask-login                  1016
Flask user session management.
justquick/django-activity-stream           1015
Generate generic activity streams from the actions on your site. Users can follow any actors' activities for personalized streams.
miguelgrinberg/Flask-SocketIO              1011
Socket.IO integration for Flask applications.
circus-tent/circus                         1009
A Process & Socket Manager built with zmq
lmacken/pyrasite                           1008
Inject code into running Python processes
getnikola/nikola                           1007
A static website and blog generator
ronnix/fabtools                            1006
Tools for writing awesome Fabric files
probonopd/AppImageKit                      1006
Using AppImageKit you can package desktop applications as AppImages that run on common Linux-based operating systems, such as RHEL, CentOS, Ubuntu, Fedora, debian and derivatives.
felixonmars/dnsmasq-china-list             1003
Accelerate Chinese Domains via Dnsmasq
scrapy/dirbot                              1003
Scrapy project to scrape public web directories (educational)
msiemens/tinydb                            1003
TinyDB is a lightweight document oriented database optimized for your happiness :)
mozilla/bleach                             1003
An easy, HTML5, whitelisting HTML sanitizer.
gabrielfalcao/lettuce                      1003
Cucumber-ish BDD for python
prakhar1989/docker-curriculum              1002
:dolphin: A comprehensive tutorial on getting started with Docker!
dellis23/ispy                              998
Monitor the output of terminals and processes.
andresriancho/w3af                         996
w3af: web application attack and audit framework, the open source web vulnerability scanner.
raelgc/scudcloud                           996
ScudCloud - Slack for Linux
ascribe/image-match                        995
Quickly search over billions of images
praw-dev/praw                              995
PRAW, an acronym for "Python Reddit API Wrapper", is a python package that allows for simple access to reddit's API.
Diaoul/subliminal                          994
Subliminal - Subtitles, faster than your thoughts
pritunl/pritunl                            987
Enterprise VPN server
pika/pika                                  987
Pure Python RabbitMQ/AMQP 0-9-1 client library
Parsely/streamparse                        986
streamparse lets you run Python code against real-time streams of data with Apache Storm.
volatilityfoundation/volatility            985
An advanced memory forensics framework
madisonmay/CommonRegex                     981
A collection of common regular expressions bundled with an easy to use interface.
yask123/Instant-Music-Downloader           981
:guitar:  Downloads Music From The Web 
editorconfig/editorconfig-vim              980
EditorConfig plugin for Vim
mothran/mongol                             975
A simple python tool to pinpoint the IP addresses of machines working for the Great Firewall of China. 
rasguanabana/ytfs                          975
YouTube File System
carljm/django-model-utils                  975
Django model mixins and utilities.
Yelp/dumb-init                             973
A minimal init system for Linux containers
jamesmawm/High-Frequency-Trading-Model-with-IB 972
A high-frequency trading model using Interactive Brokers API with pairs and mean-reversion in Python
pinry/pinry                                969
The open-source core of Pinry, a tiling image board system for people who want to save, tag, and share images, videos and webpages in an easy to skim through format.
matthewwithanm/django-imagekit             969
Automated image processing for Django. Currently v3.0
klbostee/dumbo                             968
Python module that allows one to easily write and run Hadoop programs.
google/google-api-python-client            968
yhat/db.py                                 968
db.py is an easier way to interact with your databases
Kozea/WeasyPrint                           963
WeasyPrint converts web documents (HTML with CSS, SVG, …) to PDF.
CouchPotato/CouchPotatoV1                  963
This is the old version, please use https://github.com/CouchPotato/CouchPotatoServer
gawel/pyquery                              962
A jquery-like library for python
Uberi/speech_recognition                   961
Speech recognition module for Python, supporting several engines and APIs, online and offline.
opsschool/curriculum                       959
Ops School Curriculum
nst/objc_dep                               958
Graph the import dependancies in an Objective-C project
getsentry/raven-python                     956
Raven is a Python client for Sentry (getsentry.com)
nose-devs/nose                             954
nose is nicer testing for python
wechat-python-sdk/wechat-python-sdk        954
微信公众平台 Python 开发包 (wechat-python-sdk)
roots/trellis                              947
Ansible playbooks for a WordPress LEMP stack.
justinmeister/Mario-Level-1                946
The first level of Super Mario Bros made with Python and Pygame.
kennethreitz/flask-sockets                 946
Elegant WebSockets for your Flask apps.
python-telegram-bot/python-telegram-bot    945
Not just a Python wrapper around the Telegram Bot API.
facebook/codemod                           944
Codemod is a tool/library to assist you with large-scale codebase refactors that can be partially automated but still require human oversight and occasional intervention. Codemod was developed at Facebook and released as open source.
mariocesar/sorl-thumbnail                  943
Thumbnails for Django
jonathanslenders/pymux                     942
A terminal multiplexer (like tmux) in Python
robotframework/robotframework              940
Generic test automation framework.
jrief/django-angular                       940
Let AngularJS play well with Django
kamalgill/flask-appengine-template         938
Boilerplate project template for running Flask on Google App Engine
fritzy/SleekXMPP                           937
Python 2.6+/3.1+ XMPP Library
zoofIO/flexx                               937
Python UI tookit based on web technology 
androguard/androguard                      936
Reverse engineering, Malware and goodware analysis of Android applications ... and more (ninja !)
wbond/package_control_channel              935
Default channel file for Package Control. Follow the directions at:
chineking/cola                             934
A high-level distributed crawling framework.
crossbario/crossbar                        933
Crossbar.io - WAMP application router
ottoyiu/django-cors-headers                932
Django app for handling the server headers required for Cross-Origin Resource Sharing (CORS)
gratipay/gratipay.com                      930
Payments and Payouts for Open Work
djacobs/PyAPNs                             929
Python library for interacting with the Apple Push Notification service (APNs)
mailgun/flanker                            924
Python email address and Mime parsing library
dzhibas/SublimePrettyJson                  923
plugin for Sublime Text 2 & 3 editor to pretty json
pythoncn/june                              923
June is a forum (Deprecated)
mothran/bunny                              919
Bunny is a wireless. meshing, darknet that uses 802.11 to hide its communications
mikemaccana/python-docx                    918
Reads, queries and modifies Microsoft Word 2007/2008 docx files. 
gutomaia/pyNES                             916
Python programming for Nintendo 8 bits
gruns/furl                                 913
URL manipulation made simple.
joealcorn/laboratory                       912
A Python library for carefully refactoring critical paths (and a port of Github's Scientist)
oxidane/tmuxomatic                         912
Intelligent tmux session management
graphite-project/carbon                    911
Carbon is one of the components of Graphite, and is responsible for receiving metrics over the network and writing them down to disk using a storage backend.
jelmer/dulwich                             909
Pure-Python Git implementation
Shougo/deoplete.nvim                       906
:stars: Dark powered asynchronous completion framework for neovim
coleifer/huey                              905
a little task queue for python
scipy-lectures/scipy-lecture-notes         904
Tutorial material on the scientific Python ecosystem
diafygi/letsencrypt-nosudo                 903
Free HTTPS certificates without having to trust the letsencrypt cli with sudo/root
maxme/bitcoin-arbitrage                    902
Bitcoin arbitrage - opportunity detector
pydanny/django-admin2                      900
Extendable, adaptable rewrite of django.contrib.admin
defunkt/pystache                           899
Mustache in Python
brython-dev/brython                        897
Brython (Browser Python) is an implementation of Python 3 running in the browser
secgroundzero/warberry                     896
WarBerryPi - Tactical Exploitation
getlogbook/logbook                         896
A cool logging replacement for Python.
pallets/itsdangerous                       896
Various helpers to pass trusted data to untrusted environments
Miserlou/Zappa                             894
Serverless Python Web Services
lyft/confidant                             893
Confidant: your secret keeper.
dpkp/kafka-python                          893
Python client for Apache Kafka
HIPS/autograd                              892
Efficiently computes derivatives of numpy code.
matrix-org/synapse                         892
Synapse: Matrix reference homeserver
IronLanguages/main                         891
Implementations of Python and Ruby programming languages for .NET Framework that are built on top of the Dynamic Language Runtime.
fengsp/plan                                890
Crontab jobs management in Python
ryanss/vim-hackernews                      890
Browse Hacker News inside Vim
geekan/scrapy-examples                     890
Multifarious scrapy examples.
amperka/ino                                889
Command line toolkit for working with Arduino hardware
P0cL4bs/WiFi-Pumpkin                       887
Framework for Rogue Wi-Fi Access Point Attack
jborg/attic                                887
Deduplicating backup program
andersbll/deeppy                           886
Deep learning in Python
cdhigh/KindleEar                           885
A website application running in Google app engine, deliver rss news to your kindle. generate mobi by using python, multilanguages supported.
topazproject/topaz                         884
A high performance ruby, written in RPython
ajinabraham/Mobile-Security-Framework-MobSF 883
Mobile Security Framework is an intelligent, all-in-one open source mobile application (Android/iOS) automated pen-testing framework capable of performing static, dynamic analysis and web API testing.
celery/django-celery                       882
Old Celery integration project for Django
lincolnloop/python-qrcode                  877
Python QR Code image generator
KeepSafe/android-resource-remover          877
A simple utility to remove unused resources in your Android app to lower the size of the APK. It's based on the Android lint tool output.
EasyEngine/easyengine                      877
Command-line control panel for Nginx Server to manage WordPress sites running on Nginx, PHP, MySQL, HHVM and Pagespeed.
carmaa/inception                           876
Inception is a physical memory manipulation and hacking tool exploiting PCI-based DMA. The tool can attack over FireWire, Thunderbolt, ExpressCard, PC Card and any other PCI/PCIe interfaces.
Yelp/osxcollector                          874
A forensic evidence collection & analysis toolkit for OS X
cozy/cozy-setup                            873
Cozy installation files and information
Kozea/wdb                                  872
An improbable web debugger through WebSockets
nojhan/colout                              870
Color text streams with this simple command
buckket/twtxt                              869
Decentralised, minimalist microblogging service for hackers.
jesolem/PCV                                867
Open source Python module for computer vision
thomasahle/sunfish                         866
Sunfish: a Python Chess Engine in 111 lines of code
astropy/astropy                            864
Repository for the Astropy core package
kartograph/kartograph.py                   862
Renders beautiful SVG maps in Python.
vmware/photon                              862
Minimal Linux container host
onefinestay/nameko                         861
Python framework for building microservices
Cue/scales                                 860
scales - Metrics for Python
qiwsir/ITArticles                          860
jorgebastida/gordon                        856
λ Gordon is a tool to create, wire and deploy AWS Lambdas using CloudFormation
Newmu/Theano-Tutorials                     855
Bare bones introduction to machine learning from linear regression to convolutional neural networks using Theano.
keleshev/schema                            854
Schema validation just got Pythonic
elastic/elasticsearch-py                   854
Official Python low-level client for Elasticsearch.
JelteF/PyLaTeX                             853
A Python library for creating LaTeX files
kuba/simp_le                               851
Simple Let's Encrypt Client
yandex/yandex-tank                         849
Load and performance benchmark tool
cosven/FeelUOwn                            848
nothing but the alternate, for dever
PyGithub/PyGithub                          847
Python library implementing the GitHub API v3
hayaku/hayaku                              846
Fuzzy abbreviations, support for preprocessors (Sass, Less, Stylus) and a lot of other features in easily configurable set of tools for writing CSS faster
ytisf/theZoo                               846
A repository of LIVE malwares for your own joy and pleasure
JackStouffer/Flask-Foundation              844
A solid foundation for your flask app
kliment/Printrun                           843
Pronterface, Pronsole, and Printcore - Pure Python 3d printing host software
i2y/mochi                                  843
Dynamically typed functional programming language
datamade/dedupe                            838
:id: A python library for accurate and scaleable data deduplication and entity-resolution.
Julian/jsonschema                          838
An(other) implementation of JSON Schema for Python
hexahedria/biaxial-rnn-music-composition   837
A recurrent neural network designed to generate classical music.
elastic/elasticsearch-dsl-py               837
High level Python client for Elasticsearch
insanum/gcalcli                            836
Google Calendar Command Line Interface
pre-commit/pre-commit                      836
A framework for managing and maintaining multi-language pre-commit hooks.
SmileyChris/easy-thumbnails                834
Easy thumbnails for Django
apache/libcloud                            833
Apache Libcloud is a Python library which hides differences between different cloud provider APIs and allows you to manage different cloud resources through a unified and easy to use API
errbotio/errbot                            833
Errbot is a chatbot, a daemon that connects to your favorite chat service and bring your tools and some fun into the conversation.
SpiderLabs/Responder                       832
Responder is a LLMNR, NBT-NS and MDNS poisoner, with built-in HTTP/SMB/MSSQL/FTP/LDAP rogue authentication server supporting NTLMv1/NTLMv2/LMv2, Extended Security NTLMSSP and Basic HTTP authentication. 
agiliq/merchant                            826
A Django app to accept payments from various payment processors via Pluggable backends.
apenwarr/redo                              824
Smaller, easier, more powerful, and more reliable than make.  An implementation of djb's redo.
Yelp/paasta                                823
An open, distributed platform as a service
shea256/angular-flask                      822
An AngularJS (frontend) + Flask / Python (backend) Boilerplate Application
naparuba/shinken                           822
Flexible and scalable monitoring framework
aigamedev/scikit-neuralnetwork             820
Deep neural networks without the learning cliff! Classifiers and regressors compatible with scikit-learn.
p-e-w/krill                                819
:newspaper: The hacker's way of keeping up with the world.
sabnzbd/sabnzbd                            818
SABnzbd - The automated Usenet download tool
xiaoxu193/PyTeaser                         818
Summarizes news articles
binarydud/pyres                            818
a resque clone in python
spotify/dh-virtualenv                      817
Python virtualenvs in Debian packages
Emsu/prophet                               817
Financial markets analysis framework for programmers
rkern/line_profiler                        817
Line-by-line profiling for Python
debops/debops                              817
Your Debian-based data center in a box - 
achiku/jungle                              815
AWS operations by cli should be simpler
mila-udem/blocks                           815
A Theano framework for building and training neural networks
VerbalExpressions/PythonVerbalExpressions  814
georgebrock/1pass                          813
A command line interface for 1Password
tony/tmuxp                                 810
:computer: tmux session manager built on libtmux
reviewboard/reviewboard                    810
An extensible and friendly code review tool for projects and companies of all sizes.
lunixbochs/actualvim                       808
Sublime Text 3 input mode powered by Vim
pyskell/slouchy                            808
Slouchy uses your webcam to check if you're slouching and alert you if you are. This project is still in active development and not feature complete.
celery/kombu                               808
Messaging library for Python.
gpjt/webgl-lessons                         806
https://github.com/tparisi/webgl-lessons is now the officially maintained fork for this project
git-cola/git-cola                          805
git-cola: The highly caffeinated Git GUI
andersbll/neural_artistic_style            804
Neural Artistic Style in Python
DataBrewery/cubes                          802
Light-weight Python OLAP framework for multi-dimensional data analysis
nabla-c0d3/sslyze                          801
Fast and full-featured SSL scanner.
YoSmudge/dnsyo                             799
Check your DNS against over 1000 global DNS servers
hyperopt/hyperopt                          798
Distributed Asynchronous Hyperparameter Optimization in Python
Kozea/Radicale                             797
A simple CalDAV (calendar) and CardDAV (contact) server.
9miao/Firefly                              797
Distributed Game Server Framework
SublimeText/CTags                          797
CTags support for Sublime Text 2/3
cpfair/tapiriik                            796
tapiriik keeps your fitness in sync
vim-awesome/vim-awesome                    793
Awesome Vim plugins from across the universe
PythonJS/PythonJS                          793
PythonJS development has moved to Rusthon
trustly/bankapi                            792
Secure Distributed Messaging Between Financial Institutions
jpadilla/pyjwt                             792
JSON Web Token implementation in Python
cs109/content                              790
Official content for Harvard CS109
wallproxy/wallproxy                        789
marcwebbie/passpie                         787
:closed_lock_with_key: Multiplatform command-line password manager
lxml/lxml                                  786
The lxml XML toolkit for Python
geekcomputers/Python                       784
My Python Examples
srsudar/eg                                 781
Useful examples at the command line.
spesmilo/electrum                          778
Electrum; Bitcoin thin client
biopython/biopython                        777
Official git repository for Biopython (converted from CVS)
twoscoops/django-twoscoops-project         776
The sample project layout from the book, "Two Scoops of Django 1.5 and 1.6"
pybee/toga                                 774
A Python native, OS native GUI toolkit.
nickstenning/honcho                        774
Honcho: a python clone of Foreman. For managing Procfile-based applications.
michaelliao/sinaweibopy                    773
新浪微博Python SDK
bdarnell/plop                              772
Python Low-Overhead Profiler
mozilla/playdoh                            772
Mozilla's Web application base template. Half Django, half awesomeness, half not good at math.
earle/django-bootstrap                     771
Django Form Implementation of the Twitter-Bootstrap UI
rbgirshick/fast-rcnn                       771
Fast R-CNN
openstack/horizon                          768
Horizon is a Django-based project aimed at providing a complete OpenStack Dashboard along with an extensible framework for building new dashboards from reusable components.
gunthercox/ChatterBot                      767
ChatterBot is a machine learning, conversational dialog engine.
devsnd/cherrymusic                         765
Stream your own music collection to all your devices! The easy to use free and open-source music streaming server.
Netflix/security_monkey                    763
Security Monkey
fabianp/memory_profiler                    763
Monitor Memory usage of Python code
halgari/clojure-py                         762
A implementation of Clojure in pure (dynamic) Python
BurntSushi/nflgame                         756
An API to retrieve and read NFL Game Center JSON data. It can work with real-time data, which can be used for fantasy football.
karan/slack-overflow                       754
A programmer's best friend, now in Slack.
pyjs/pyjs                                  753
Pyjs canonical sources. Start here!
evonove/django-oauth-toolkit               753
OAuth2 goodies for the Djangonauts!
mhartl/rails_tutorial_sublime_text         753
Sublime Text 2 setup used in the Ruby on Rails Tutorial
python-excel/xlrd                          752
Library for developers to extract data from Microsoft Excel (tm) spreadsheet files
disqus/gargoyle                            752
Feature switches in Django
jmcnamara/XlsxWriter                       751
A Python module for creating Excel XLSX files.
ReactiveX/RxPY                             746
Reactive Extensions for Python
peterbe/mincss                             746
Tool for finding out which CSS selectors you're NOT using.
maltize/sublime-text-2-ruby-tests          745
Sublime Text 2 plugin for running ruby tests! (Unit, RSpec, Cucumber)
spulec/freezegun                           745
Let your Python tests travel through time
conda/conda                                743
OS-agnostic, system-level binary package manager and ecosystem
themadinventor/esptool                     742
ESP8266 ROM Bootloader utility
scrapinghub/splash                         739
Lightweight, scriptable browser as a service with an HTTP API
gbeced/pyalgotrade                         737
Python Algorithmic Trading Library
mwhite/resume                              737
Markdown -> PDF/HTML resumé generator
michael-lazar/rtv                          736
Browse Reddit from your terminal
tarekziade/boom                            736
A replacement for AB (Apache Bench)
moxie0/sslstrip                            733
A tool for exploiting Moxie Marlinspike's SSL "stripping" attack.
viper-framework/viper                      733
Binary analysis and management framework
owocki/pytrader                            732
cryptocurrency trading robot
Maratyszcza/PeachPy                        730
x86-64 assembler embedded in Python
miracle2k/webassets                        730
Asset management for Python web development.
r8/vagrant-lamp                            729
My default LAMP development stack for Vagrant
syrusakbary/gdom                           729
DOM Traversing and Scraping using GraphQL
Veil-Framework/Veil-Evasion                729
Veil-Evasion is a tool used to generate payloads that bypass antivirus solutions
behave/behave                              728
BDD, Python style.
bndr/pipreqs                               728
pipreqs - Generate pip requirements.txt file based on imports of any project
mrjoes/sockjs-tornado                      727
WebSocket emulation - Python server
munki/munki                                727
Managed software installation for OS X —
metabrainz/picard                          726
MusicBrainz Picard
dask/dask                                  726
Versatile parallel programming with task scheduling
lanyrd/mysql-postgresql-converter          724
Lanyrd's MySQL to PostgreSQL conversion script
kmmbvnr/django-jenkins                     723
Plug and play continuous integration with django and jenkins
jbtule/cdto                                723
Finder Toolbar app to open the current directory in the Terminal (or iTerm, X11)
eBay/restcommander                         722
Fast Parallel Async HTTP client as a Service to monitor and manage 10,000 web servers. (Java+Akka)
compjour/search-script-scrape              721
101 real world web scraping exercises in Python 3 for data journalists
tensorflow/magenta                         720
Magenta: Music and Art Generation with Machine Intelligence
bradjasper/django-jsonfield                717
A reusable JSONField model for Django to store ad-hoc data
dagwieers/unoconv                          717
Universal Office Converter - Convert between any document format supported by LibreOffice/OpenOffice.
graphql-python/graphene                    716
GraphQL framework for Python
cloudera/ibis                              715
Productivity-centric Python data analysis framework for SQL systems and the Hadoop platform. Co-founded by the creator of pandas
mitsuhiko/pipsi                            713
pip script installer
pimusicbox/pimusicbox                      713
An image (SD-card) to turn the Raspberry Pi into an easy to use MusicBox with Spotify playback and AirTunes streaming
joblib/joblib                              712
Python function as pipeline jobs.
ivanov/vim-ipython                         712
A two-way integration between Vim and IPython 0.11+
sockeye44/instavpn                         711
the most user-friendly L2TP/IPsec VPN server
jleclanche/django-push-notifications       710
Send push notifications to mobile devices through GCM or APNS in Django.
tomchristie/flask-api                      710
Browsable web APIs for Flask
zyqf/DNS                                   709
PandaDNS - Build your own DNS server quickly !
spulec/moto                                709
Moto is a library that allows your python tests to easily mock out the boto library
laiwei/thepast                             708
thepast.me
ansible/ansible-modules-core               708
Ansible modules - these modules ship with ansible
mbr/flask-bootstrap                        708
Ready-to-use Twitter-bootstrap for use in Flask.
lepture/flask-oauthlib                     708
OAuthlib implementation for Flask.
ninja-ide/ninja-ide                        707
{Ninja-IDE Is Not Just Another IDE}
mjhea0/flaskr-tdd                          707
 Flaskr: Intro to Flask, Test Driven Development (TDD), and jQuery
sloria/doitlive                            707
Because sometimes you need to do it live
JonathanSalwan/ROPgadget                   705
This tool lets you search your gadgets on your binaries to facilitate your ROP exploitation. ROPgadget supports ELF, PE and Mach-O format on x86, x64, ARM, ARM64, PowerPC, SPARC and MIPS architectures. 
hellerve/programming-talks                 704
Awesome & Interesting Talks concerning Programming
centrifugal/centrifuge                     704
Simple real-time messaging in web applications. Migrated to Go language, see https://github.com/centrifugal/centrifugo
openstack/neutron                          703
Neutron is a virtual network service for Openstack.
thiderman/doge                             703
wow very terminal doge
pytest-dev/pytest                          702
The pytest framework makes it easy to write small tests, yet scales to support complex functional testing
SublimeText/TrailingSpaces                 700
Highlight trailing spaces and delete them in a flash.
ponyorm/pony                               700
Pony Object Relational Mapper
vvk-ehk/evalimine                          699
e-hääletamise tarkvara
rossem/RedditStorage                       699
Store files onto reddit subreddits.
pyload/pyload                              697
A free and open source personal cloud storage as well as download manager for all kind of operating systems and devices, designed to be extremely lightweight and runnable on personal pc or headless server.
mattupstate/flask-security                 697
Quick and simple security for Flask applications
django-nose/django-nose                    695
Django test runner using nose
urwid/urwid                                694
Console user interface library for Python (official repo)
coto/gae-boilerplate                       693
Google App Engine Boilerplate
MagicStack/MagicPython                     691
Cutting edge Python syntax highlighter for Sublime Text, Atom and Visual Studio Code. Used by GitHub to highlight your Python code!
pcmanus/ccm                                691
A script to easily create and destroy an Apache Cassandra cluster on localhost
muricoca/crab                              690
Crab is a flexible, fast recommender engine for Python that integrates classic information filtering recommendation algorithms in the world of scientific Python packages (numpy, scipy, matplotlib).
buildinspace/peru                          689
a tool for including other people's code in your projects
asciimoo/searx                             688
A privacy-respecting, hackable metasearch engine
kayhayen/Nuitka                            688
Official mirror of Nuitka as from http://nuitka.net
driverdan/dropship                         688
Instantly transfer files between Dropbox accounts using only their hashes.
eliben/pycparser                           687
:snake: Complete C99 parser in pure Python
peterhudec/authomatic                      687
Simple yet powerful authorization / authentication client library for Python web applications.
orf/gping                                  686
Ping, but with a graph
iambus/youku-lixian                        686
优酷下载脚本,顺便支持其他……
msanders/cider                             686
Hassle-free bootstrapping with Homebrew.
gregs1104/pgtune                           685
PostgreSQL configuration wizard
kevin1024/vcrpy                            685
Automatically mock your HTTP interactions to simplify and speed up testing
ckreibich/scholar.py                       685
A parser for Google Scholar, written in Python
shadowsocks/ChinaDNS-Python                685
Protect yourself against DNS poisoning in China.
spragunr/deep_q_rl                         685
Theano-based implementation of Deep Q-learning
dropbox/changes                            684
A dashboard for your code. A build system.
StijnMiroslav/top-starred-devs-and-repos-to-follow 683
The Top-Starred Python GitHub Devs, Orgs, and Repos to Follow (All-Time and Trending)
robdmc/pandashells                         682
:panda_face: Bringing the python data stack to the shell prompt
ryankiros/skip-thoughts                    681
Sent2Vec encoder and training code from the paper "Skip-Thought Vectors"
stasinopoulos/commix                       681
Automated All-in-One OS Command Injection and Exploitation Tool
TheRook/subbrute                           681
A DNS meta-query spider that enumerates DNS records, and subdomains.
wummel/linkchecker                         681
check links in web documents or full websites
Komodo/KomodoEdit                          680
Komodo Edit is a fast and free multi-language code editor. Written in JS, Python, C++ and based on the Mozilla platform.
yosinski/deep-visualization-toolbox        679
DeepVis Toolbox
jenskutilek/FiraSystemFontReplacement      679
Modified version of the Fira Sans fonts to replace the default system font on Mac OS X 10.10 and 10.11
GetBlimp/django-rest-framework-jwt         678
JSON Web Token Authentication support for Django REST Framework
jupyter/nbviewer                           677
Nbconvert as a webservice (rendering ipynb to static HTML)
Lawouach/WebSocket-for-Python              675
WebSocket client and server library for Python 2 and 3 as well as PyPy (ws4py 0.3.4)
sphinx-doc/sphinx                          675
Main repository for the Sphinx documentation builder
angr/angr                                  675
The next-generation binary analysis platform from UC Santa Barbara's Seclab!
DrkSephy/django-hackathon-starter          674
A boilerplate for Django web applications
graphite-project/whisper                   673
Whisper is a file-based time-series database format for Graphite.
infobyte/faraday                           671
Collaborative Penetration Test and Vulnerability Management Platform
JasperSnoek/spearmint                      669
Spearmint is a package to perform Bayesian optimization according to the algorithms outlined in the paper:  Practical Bayesian Optimization of Machine Learning Algorithms. Jasper Snoek, Hugo Larochelle and Ryan P. Adams.  Advances in Neural Information Processing Systems, 2012 
django-silk/silk                           669
Silky smooth profiling for Django
dnouri/nolearn                             668
Abstractions around neural net libraries, most notably Lasagne.
naspeh/mailur                              668
The future replacement for Gmail.
signalfx/maestro-ng                        665
Orchestration of Docker-based, multi-host environments
m57/dnsteal                                665
DNS Exfiltration tool for stealthily sending files over DNS requests.
programa-stic/barf-project                 665
BARF : A multiplatform open source Binary Analysis and Reverse engineering Framework
sh4nks/flaskbb                             664
A forum software written in flask
sopel-irc/sopel                            664
Formerly Willie. An easy-to-use and highly extensible IRC Bot framework
anishathalye/dotbot                        664
A tool that bootstraps your dotfiles • Looking for feedback and contributors for Dotbot 2.0 -- see Issue #35
bfontaine/term2048                         664
:tada: 2048 in your terminal
getpelican/pelican-plugins                 663
Collection of plugins for the Pelican static site generator
yadayada/acd_cli                           663
A command line interface and FUSE filesystem for Amazon Cloud Drive
lepture/mistune                            663
The fastest markdown parser in pure Python with renderer feature, inspired by marked and misaka.
feincms/feincms                            658
A Django-based CMS with a focus on extensibility and concise code
hit9/PyZh                                  657
一起写Python文章,一起看Python文章 - 利用readthedocs的Python技术文章的收集和翻译。
xenith/django-base-template                657
A Django 1.7 base template with HTML5Boilerplate and Twitter Bootstrap
rusthon/Rusthon                            656
multi-lang transpiler, compiler frontend.
osmc/osmc                                  656
OSMC (Open Source Media Center) is a free and open source media center distribution
pilotmoon/PopClip-Extensions               655
Documentation and source code PopClip extensions.
jimmyxu/chnroutes                          654
Forked from https://chnroutes.googlecode.com/
kmmbvnr/django-fsm                         651
Django friendly finite state machine support
hubert3/iSniff-GPS                         651
Passive sniffing tool for capturing and visualising WiFi location data disclosed by iOS devices
nickoala/telepot                           651
Python framework for Telegram Bot API
sebleier/django-redis-cache                651
A Redis cache backend for django
byt3bl33d3r/gcat                           650
A fully featured backdoor that uses Gmail as a C&C server
smarr/latex-to-html5                       650
Scripts for Latex to HTML5 conversion
twilio/twilio-python                       650
A Python module for communicating with the Twilio API and generating TwiML. Need help? Post your questions to http://getsatisfaction.com/twilio or email us at help@twilio.com
Urinx/WeixinBot                            649
网页版微信API,包含终端版微信及微信机器人
gregmuellegger/django-floppyforms          648
Full control of form rendering in the templates.
Dobiasd/programming-language-subreddits-and-their-choice-of-words 648
How do the different communities talk?
mongolab/dex                               648
Index and query analyzer for MongoDB: compares MongoDB log files and index entries to make index recommendations
pinterest/mysql_utils                      647
Pinterest MySQL Management Tools
KarimJedda/whatsappcli                     647
Control your server from Whatsapp
desaster/kippo                             647
Kippo - SSH Honeypot
SickRage/SickRage                          647
The new home of the SickRage community
drzoidberg33/plexpy                        646
A Python based monitoring and tracking tool for Plex Media Server.
andialbrecht/sqlparse                      644
A non-validating SQL parser module for Python
charlesthomas/magpie                       644
Git-backed Evernote replacement
hypothesis/h                               643
The Internet, peer reviewed.
translate/pootle                           643
Online translation tool
twissandra/twissandra                      643
Twissandra is an example project, created to learn and demonstrate how to use Cassandra. Running the project will present a website that has similar functionality to Twitter.
ahupp/python-magic                         642
A python wrapper for libmagic
yourlabs/django-autocomplete-light         641
A fresh approach to autocomplete implementations, specially for Django. Status: v3 stable, 2.x.x stable, 1.x.x deprecated. Please DO regularely ping us with your link at #yourlabs IRC channel
rubik/radon                                641
Various code metrics for Python code
isnowfy/pydown                             641
An HTML5 presentation builder written by python
mwrlabs/drozer                             641
The Leading Security Assessment Framework for Android.
wooey/Wooey                                640
A Django app which creates automatic web UIs for Python scripts.
jazzband/django-constance                  640
Dynamic Django settings.
jfinkels/flask-restless                    640
A Flask extension for creating simple ReSTful JSON APIs from SQLAlchemy models.
divio/django-filer                         640
File and Image Management Application for django
audreyr/cookiecutter-pypackage             639
Cookiecutter template for a Python package.
byt3bl33d3r/CrackMapExec                   638
A swiss army knife for pentesting Windows/Active Directory environments
django-nonrel/mongodb-engine               638
Django MongoDB Backend
jrnewell/spotify-ripper                    638
Command-line ripper for Spotify
paralax/awesome-honeypots                  638
an awesome list of honeypot resources
anishathalye/neural-style                  637
Neural style in TensorFlow! • http://www.anishathalye.com/2015/12/19/an-ai-that-can-mimic-any-artist/ • https://git.io/style
overshard/pinry                            637
Pinry's repository has moved to
adamn/python-webkit2png                    637
Python script that takes screenshots (browsershots) using webkit
eBay/bayesian-belief-networks              637
Pythonic Bayesian Belief Network Package, supporting creation of and exact inference on Bayesian Belief Networks specified as pure python functions.
antiboredom/audiogrep                      636
Creates audio supercuts.
simplejson/simplejson                      636
simplejson is a simple, fast, extensible JSON encoder/decoder for Python 
nitishsrivastava/deepnet                   635
Implementation of some deep learning algorithms.
django-import-export/django-import-export  635
Django application and library for importing and exporting data with admin integration.
iamaziz/PyDataset                          635
Instant access to many datasets.
srusskih/SublimeJEDI                       634
awesome Python autocompletion with SublimeText
os/slacker                                 634
Full-featured Python interface for the Slack API
GoogleCloudPlatform/PerfKitBenchmarker     633
Perfkit Benchmarker contains set of benchmarks to measure and compare cloud offerings. The benchmarks use defaults to reflect what most users will see. PerfKit Benchmarker is licensed under the Apache 2 license terms. Please make sure to read, understand and agree to the terms of the LICENSE and CONTRIBUTING files before proceeding.
commonsense/conceptnet5                    633
Code for building ConceptNet from raw data.
pybuilder/pybuilder                        633
Continuous build tool for Python.
cea-sec/miasm                              633
Reverse engineering framework in Python
markfinger/python-react                    632
Server-side rendering of React components
realpython/python-scripts                  632
because i'm tired of gists
python/pythondotorg                        631
Source code for python.org
gak/pycallgraph                            630
pycallgraph is a Python module that creates call graphs for Python programs.
thauber/django-schedule                    629
A calendaring app for Django.  It is now stable, Please feel free to use it now. Active development has been taken over by bartekgorny.
alienhard/SublimeAllAutocomplete           628
Extend Sublime autocompletion to find matches in all open files of the current window
mirumee/satchless                          628
E-commerce for Python
truebit/xUnique                            628
merge Xcode project file is so easy
LoyaltyNZ/alchemy-framework                627
Alchemy is a framework for creating highly available systems that are built from micro-services
hatRiot/zarp                               627
Network Attack Tool
rbgirshick/py-faster-rcnn                  627
Faster R-CNN (Python implementation) -- see https://github.com/ShaoqingRen/faster_rcnn for the official MATLAB version
timothycrosley/isort                       626
A Python utility / library to sort imports.
jaraco/path.py                             625
"Path" object conveniently wrapping assorted file/path-related functionality
formspree/formspree                        622
Easy HTML form without PHP or JavaScript
jh00nbr/Routerhunter-2.0                   621
Testing vulnerabilities in devices and routers connected to the Internet.
rholder/retrying                           621
Retrying is an Apache 2.0 licensed general-purpose retrying library, written in Python, to simplify the task of adding retry behavior to just about anything.
martinrusev/imbox                          620
Python IMAP for Human beings
aaugustin/django-c10k-demo                 620
10 000 concurrent real-time connections to Django
laramies/theHarvester                      619
E-mail, subdomain and people names harvester
np1/mps                                    619
Terminal based MP3 search, playback and download
simonwagner/mergepbx                       617
script for merging XCode project files in git
flashingpumpkin/django-socialregistration  617
Combining OpenID, OAuth and FacebookConnect signup in one application
Capgemini/Apollo                           617
:rocket: An open-source platform for cloud native applications based on Apache Mesos and Docker.
django-cache-machine/django-cache-machine  617
Automatic caching and invalidation for Django models through the ORM.
brainsik/virtualenv-burrito                616
One command to have a working virtualenv + virtualenvwrapper environment.
EvilCult/Video-Downloader                  616
获取youku,letv,sohu,tudou,bilibili,acfun,iqiyi等视频源文件地址,提供mac&win&linux独立App。
FriendCode/gittle                          615
Pythonic Git for Humans
jyapayne/Web2Executable                    615
Uses NW.js to generate "native" apps for already existing web apps.
paul-nechifor/ohmu                         614
View space usage in your terminal.
ilektrojohn/creepy                         613
A geolocation OSINT tool. Offers geolocation information gathering through social networking platforms.
kvh/ramp                                   612
Rapid Machine Learning Prototyping in Python
saghul/pythonz                             611
Python installation manager supporting CPython, Stackless, PyPy and Jython
mongodb/motor                              611
arguman/arguman.org                        611
Argument analysis and mapping platform
erikrose/blessings                         610
A thin, practical wrapper around terminal capabilities in Python
simpleai-team/simpleai                     610
simple artificial intelligence utilities
toscanini/maestro                          609
Container orchestration for Docker environments
benmatselby/sublime-phpcs                  607
PHP CodeSniffer, PHP Coding Standard Fixer, Linter and Mess Detector Support for Sublime Text
condemil/Gist                              607
Sublime Text plugin for creating new Gists from selected text
syrusakbary/pyjade                         606
Jade syntax adapter for Django, Jinja2 and Mako templates
Exa-Networks/exabgp                        606
The BGP swiss army knife of networking
lyst/lightfm                               605
A Python implementation of LightFM, a hybrid recommendation algorithm.
tomchristie/django-vanilla-views           604
Beautifully simple class-based views.
msgpack/msgpack-python                     602
MessagePack serializer implementation for Python msgpack.org[Python]
FogCreek/WebPutty                          601
WebPutty is a simple CSS editing and hosting service that you can run on Google App Engine.
garnaat/kappa                              601
What precedes Lambda
jdf/processing.py                          601
Write Processing sketches in Python
alecthomas/voluptuous                      600
Voluptuous, despite the name, is a Python data validation library.
joerick/pyinstrument                       600
Call stack profiler for Python. Inspired by Apple's Instruments.app
F-Secure/see                               599
Sandboxed Execution Environment